This vacancy is posted as part of RegMedXB, which stands for “Regenerative Medicine Crossing Borders”. RegMedXB is a virtual institute composed of universities, health foundations, governments and private companies in the Netherlands and Belgium. The partners work together to tackle some of the greatest challenges in regenerative medicine, while building a community of researchers and companies to realize health and economic benefits. The RegMedXB Cardiac Moonshot program aims at developing innovative strategies to regenerate the tissues of the heart, including the myocardium, heart valves and blood vessels.
The current project concentrates on preserving and regenerating heart valve function under non-physiological loading conditions. For this you will investigate the structural and biological remodeling of heart valves using a combination of experimental and computational research.
The experimental research will focus on establishing an ex vivo platform to investigate the remodeling and functionality of heart valves under various hemodynamic conditions.
The computational part focuses on simulating valve remodeling, with the aim of understanding and predicting experimental outcomes, and extrapolating findings to relevant in vivo situations.
If you are fascinated by the engineering aspects of regenerative medicine and eager to develop innovate models and strategies that will advance cardiovascular regeneration, we invite you to join us in this challenge. You will collaborate intensively with our partners in the RegMed-XB Cardiac Moonshot consortium, in particular with the University Medical Centers in Leiden and Utrecht on ex vivo tissue remodeling, and with other TU/e groups on computational modeling and tissue engineering.
Information about the RegMedXB program can be found on: www.regmedxb.com
Information about the Biomedical Engineering department can be found at: https://www.tue.nl/en/university/departments/biomedical-engineering/
Information about the Soft Tissue Engineering & Mechanobiology group can be found on: www.tue.nl/STEM
Do you recognize yourself in this profile and would you like to know more? Please contact:
For information about terms of employment, click here or contact Sascha Sanchez, HR advisor, s.j.m.g.sanchez.van.oort[at]tue.nl or HRServices.Gemini[at]tue.nl
Please visit www.tue.nl/jobs to find out more about working at TU/e!
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About Eindhoven University of Technology (TU/e)
TU/e is a University of Technology with a focus on Health, Energy and Mobility. Within the Health area, several departments cooperate on topics such as Chemical Biology, Regenerative Medicine, Computational Biology, and Biosensing, with close links to healthcare and industry. TU/e is an open and inclusive university with short communication lines. The people are curious, collaborative, and strive for excellence. TU/e enables its academic staff to develop research and education at an internationally renowned level. Our lively campus community facilitates connections between staff and students, in an open, friendly, vibrant atmosphere that welcomes and inspires.
The Department of Biomedical Engineering (BME) offers a research driven BME Bachelor program and Masters in Biomedical Engineering and Medical Engineering in its Graduate Program. Its research areas range from Molecular Bioengineering and Imaging, Biomechanics and Tissue Engineering to Biomedical Imaging and Modelling. The department has more than 800 students and up to 200 tenured and non-tenured employees.
The research will be mainly conducted within the Soft Tissue Engineering and Mechanobiology (STEM) group in the Department of Biomedical Engineering.
The STEM group, headed by prof.dr. C.V.C. Bouten, concentrates on the engineering of soft tissues, aimed at either the replacement of diseased or malformed tissues, or the development of in-vitro model systems of developing tissues. Important fundamental research lines concern the biophysical (stem) cell niche and the mechanobiology of tissue organization. Results are used to design novel approaches of in-situ tissue regeneration, with principle application in the cardiovascular area (heart valves and vessels) and organ regeneration (heart, kidney). The group houses the Cell and Tissue Engineering laboratory, a shared research infrastructure operating at the international forefront of the engineering of living, load-bearing tissues.