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PhD Developing an image-based simulation tool for cardiovascular biomechanics

PhD Developing an image-based simulation tool for cardiovascular biomechanics

The Eindhoven University of Technology (TU/e), Department of Mechanical Engineering has a vacancy for a PhD Student Development of an image-based simulation tool for cardiovascular biomechanics (V35.4306) in the Multiscale Engineering Fluid Dynamics group.
Position
PhD-student
Department(s)
Department of Biomedical Engineering, Department of Mechanical Engineering
FTE
1,0
Date off
31/03/2020
Reference number
V35.4306

Job description

Job description

Ventricular tachycardias (VTs) are heart rhythm disorders leading to an abnormal increase in heart rate, even during rest. Successful treatment or prevention of VTs by implantable defibrillators (ICD) and catheter ablation is hampered by the complexity and patient-specificity of the disorder. In a collaboration between the TU/e, Philips Research, and the Catharina Hospital, the research program Computational-model-based decision support for patients at risk for sustained ventricular tachycardias will develop a computational model that makes use of the patient’s data to predict the risk of VTs and supports decision of the best personalized treatment based on simulating the (interaction between) electrophysiology and mechanical behavior for patient-specific models.

The research program is divided into four interlinked sub-projects of which one project is advertised here. The objective of this project is to develop a new patient-specific simulation tool based on advanced numerical techniques such as higher-order and isogeometric finite element methods and immersed simulation concepts. As part of this project, the generation of analysis-suitable three-dimensional heart models based on scan-data is considered, which will be based on novel robust advanced discretization techniques. Using the developed simulation tool, mechanical and electro-mechanical simulations will be conducted to derive the effective electrophysiological properties of a heart model. This requires a strong cooperation with the second PhD student within this program. Specific attention will be paid to the visualization of the results on the patient-specific geometry, as to allow for optimal interpretation and validation of the results in the clinical sub-projects of the research program.

Job requirements

Job requirements

We are looking for an experienced candidate with an MSc degree in mechanical engineering, physics, applied mathematics or similar. The candidate should have knowledge of continuum mechanics and numerical methods (such as the finite element method) combined with strong programming and mathematical skills and a good physical intuition. The ideal candidate has excellent scientific skills as well as excellent soft skills related to verbal and written communication.

Conditions of employment

We offer a challenging job for four years in a highly motivated team at a dynamic and ambitious University. You will be part of a highly profiled multidisciplinary collaboration where expertise of a variety of disciplines comes together. The TU/e is located in one of the smartest regions of the world and part of the European technology hotspot ‘Brainport Eindhoven’; well-known because of many high-tech industries and start-ups. A place to be for talented scientists!

The gross monthly salary in accordance with the Collective Labor Agreement of the Dutch Universities (CAO NU), starts with   € 2.325,- in the first year to € 2.972,- in the fourth year. Besides this the TU/e has holiday- and end-of the-year-allowances, an excellent package of attractive benefits for employees and a modern sports complex. Assistance for finding accommodation can be given. Especially for PhD students the TU/e also offers opportunities for personal development. We do this by offering every PhD student a series of courses that are part of the Proof program as an excellent addition to your scientific education.

Information and application

More information about the project can be obtained from Dr. C.V. Verhoosel, email: c.v.verhoosel[at]tue.nl or Dr. O. van der Sluis, email: o.v.d.sluis[at]tue.nl. Personnel information can be obtained from Mrs. Hind Boulgalag, HR Advisor, email: h.boulgalag[at]tue.nl.

Information about the employment conditions can be found here.

You can respond to this vacancy via our application page www.tue.nl/jobs by clicking on the button "Solliciteer op deze vacature / Apply for this job" including:

  • a cover letter (stating personal goal and research interests connecting to one or more of the topics defined above),
  • a complete Curriculum Vitae (including a list of publications if any),
  • transcripts of BSc and MSc degrees,
  • at least one recommendation letter.

We do not respond to applications that are sent to us in a different way.

Both national and international applications to this advertisement are appreciated. Review of applications will begin immediately and continue until the position is filled. Promising candidates will be contacted by email.